Factors influencing supercritical carbon dioxide extraction include the density, entrainer, particle size, volume and so on
The density of A.
Solvent strength is related to the density of supercritical fluid. At a given temperature, the density (pressure) increases, increasing solvent strength and solubility.
B. entrainer
Is suitable for the majority of the supercritical fluid extraction solvent is a polar solvent, which is beneficial to selective extraction, but limits its applications to the larger polar solute. So can add a small amount of entrainer in the fluid, so as to change the polarity of solvent. The most commonly used to extraction of supercritical fluid carbon dioxide, by joining entrainer can be applied to larger polar compounds. Someone is 10 mpa pressure (equal to about 100 atmospheres), with different concentrations of ethanol entrainer, Snow in medicine ganoderma lucidum was studied in the extraction of these three kinds of ingredients. Add certain entrainer supercritical carbon dioxide extraction solvent can create generally not conditions, greatly improve the yield. This for the extraction of valuable medicinal ingredients, high value for development of industrialization. Commonly used ethanol entrainer, urea, acetone, hexane and water and so on.
C. granularity
Particle size can affect extraction yield.
D. fluid volume
The molecular structure of the extract is associated with the volume of the supercritical fluid. Scientists will be pressurized heating to 68.8 ATM, 40 ℃ after extraction of 50 grams of leaves of lutein and carotene. To get the lutein, the recovery rate of 50%, to 2.1 L supercritical carbon dioxide; In order to obtain a 95% recovery rate, 33.6L of supercritical carbon dioxide is required, while the high solubility of carotene in carbon dioxide only needs 1.4L to achieve a 95% recovery rate
Carbon dioxide extraction